Research Department


Our research facility is a 10,000 square foot office located in the central region of San Diego, 3 miles away from Rady Childrens Hospital and Sharp Memorial Hospital.

RESEARCH PERSONNEL:

  • Four Board Certified Allergists/Clinical Immunologists
  • Three Certified Clinical Research Coordinators
  • One Administrative Clinical Research Coordinator

RESEARCH HISTORY:

  • Completion of over 690 clinical research projects; Phase I, II, III and IV
  • Clinical trials in pediatric, adult and senior populations
  • Numerous studies completed in patients with diseases of the upper and lower airway including rhinitis, sinusitis and asthma and in studies of the central nervous and gastrointestinal systems and infectious diseases
  • In the past 40 years, Allergy and Asthma Medical Group and Research Center has contracted with numerous pharmaceutical companies including: Abbott, Alcon, Alexza, Allux, Amgen, Antigen Labs, Apotex, Armstrong, Arris, Astellas, AstraZeneca (Astra, AstraMerck, ICI, Zeneca), Baker Norton, Berlex, Boehringer Ingelheim, Boots, Bristol-Myers Squibb, Capnia, Chiesi, Clay Park, Cooper, Critical Therapeutics, Dey, Dura, Ferraris, Fisons, Flemmington, Forest, Genentech, GlaxoSmithKline (Glaxo-Wellcome, Glaxo, Burroughs Wellcome, SmithKline Beecham), Greer, Hoffmann-LaRoche (Syntex), Immulogic, Immunetech, Immunex, Inspire, Janssen, Johnson & Johnson (Mead Johnson), Knoll, KOS, Eli Lilly, Liposome Technology, MAP Pharmaceuticals, Mast, McNeil Consumer Products, MEDA (MedPointe, Wallace), Medeva, Medicinova, MedImunne, Merck, Merck Sharp and Dohme, Miles, Millennium (Leukosite), Muro, Nastech, Naryx, Neurogen, Novartis (Sandoz, Ciba Geigy), Nycomed (Altana), Pennwalt, Pfizer (Parke-Davis, Warner Lambert), Pharmaxis, Proctor & Gamble, Rigel, Roberts, Sanofi-Aventis, (Aventis, Fisons, Hoechst Roussel, Marion, Merrell Dow, Rhone-Poulenc Rorer, Sanofi, Sterling, Winthrop), Schering-Plough (Schering, Key),Schering-Plough Integrated Therapeutics Group, Searle, Shinogi, SkyePharma, State of California, Sunovion (Sepracor), Synergen, TAP, TEVA (IVAX), 3M Pharmaceuticals, UCB, VentiRx, VOCEL, Whitehall-Robins, Winston, Wyeth (Wyeth-Ayerst), and Zambon.
  • Contracted with many major Contract Research Organizations

SITE CAPABILITIES:

  • Ability to create, design, manage and conduct inside and outside of specialty studies
  • Aggressive recruitment strategies (including TV, print media and Internet)
  • Ongoing community service and visibility as clinical research advocates
  • Research physician available 24 hours
  • Pharmacokinetic studies on adult and pediatric patients
  • Phase I capabilities with 24 hour housing and evaluations
  • Twenty-four hour clinical symptom, adverse effect and laboratory evaluations
  • Outdoor park for group acute symptom evaluation
  • Nasal cytology (central laboratory for interpreting cytograms for multicenter studies)
  • Mediator measurements including: histamine, tryptase, eosinophil cationic protein and albumin
  • Biochemistry measurements including: IFN, TNF, adhesion molecules, proinflammatory mediators, cytokines, chemokines and airway inflammation analysis (nitric oxide)
  • Olfactory testing and ciliary function; rhinomanometry and fiberoptic rhinopharyngoscopy
  • Immediate hypersensitivity testing
  • Antigen, histamine and methacholine challenges for rhinitis and asthma
  • Pulmonary function testing
  • Exercise treadmill testing
  • ECG and 24 hour holter ECG
  • Exposure Unit for Fel d 1 (cat)
  • Sublingual Immunotherapy (SLIT)
  • Subucaneous Immunotherapy (SCIT)
  • Data base (Study Manager)
  • Computer, fax and remote data entry, high speed internet connection (DSL)

AVAILABLE RESOURCES:

  • Imaging facilities: x-ray, computerized tomography and bone densitometry
  • Otolaryngologist, ophthalmologist, gastroenterologist, cardiologist, pediatricians, pediatric specialists and family practitioners
  • Certified clinical laboratory (local and central)
  • Institutional Review Board (local and central)

CONSULTANTS:

  • Assisted pharmaceutical companies in all phases of protocol development, implementation, data analysis and oral/written presentations to scientific communities and the Food and Drug Administration (FDA)
  • Past membership on a FDA Advisory Board
  • Past memberships on an Institutional Review Board
  • Over 2000 presentations and publications on pharmacotherapy